Pokemon Sleep is absolutely its own game, but of course, it carries over many features and functions from the main Pokemon series. One of those is Natures. When you catch a Pokemon, it will have a Nature attached to it. This determines what stat receives an increase and which one is decreased.
There are over a dozen Natures in Pokemon Sleep. Each of them have their upsides and downsides. You'll want your Pokemon to get the most out of their increased stat without having too much negativity to worry about on the other end. That makes Speed of Help and Main Skill increases the most valuable.
8 Naughty
The Naughty Nature in Pokemon Sleep is good for helper Pokemon. It decreases the Main Skill chance, but does increase Speed of Help. Set one with Naughty as the helper and they will be able to contribute faster.
The Natures that increase Speed of Help will always have a decreased stat alongside it, but being able to help you quicker is invaluable. It's all about determining which stat decrease is the least damaging one for your efforts.
7 Brave
Brave is a Speed of Help stat in Pokemon Sleep. This Nature is one of four that increase your Pokemon's Speed of Help stat. This means that, as a Helper Pokemon, they will gather Berries for Snorlax and other ingredients quicker.
If your Pokemon comes with the Brave Nature, you'll see a decrease in its ability to gain EXP. That makes it one of the less desirable Speed of Help Natures, though it is still ahead of many others. EXP gains might take longer, but it just means you get to spend more time with that specific Pokemon partner.
6 Adamant
Pokemon in Pokemon Sleep come with a Main Skill. This is basically what the Pokemon is good at, such as finding extra Berries or even additional Ingredients. For Adamant, if you get it on a Pokemon whose Main Skill provides a chance of extra Ingredients, you're in for a good time.
This is because the Adamant Nature increases the Pokemon's Speed of Help. It decreases its Ingredient Finding, but with the Main Skill enabled, it will still put it above where it started originally. So, you will receive slightly more Ingredients at a faster rate.
5 Lonely
Lonely is the fourth and final Speed of Help Nature in Pokemon Sleep, and a great one beginners can hope for. It is also the best Nature with that type of increase. It doesn't take down any other stat with major importance. You'll just find Energy Recovery taking a hit with the Lonely Nature.
Pokemon lose energy throughout the day as they perform tasks. This doesn't change the rate that energy is reduced, just the rate at which it recovers. Therefore, you can get all of the Pokemon's helpful benefits then let it hang out for the rest of the day. Or you can use an item like an Energy Pillow to get its energy back up that way.
4 Calm
After the Speed of Help Natures in Pokemon Sleep, the best you can hope for is a Nature with a Main Skill increase. And that starts with the Calm Nature. Speed of Help decreases with Calm, so that puts it at the back of the line for Main Skill Natures.
It still is very effective if available, however. The increased chance of your Pokemon partner using their Main Skill is invaluable. You could end up with bonus energy, higher Strength for Snorlax, or even a load of Dream Shards.
3 Careful
Careful is Main Skill increase Nature. The negative from this one is Ingredient Finding, meaning that statistic will be lowered. It isn't a terrible tradeoff, but finding Ingredients can take some time. Without a Speed of Help increase like you'd find with other Natures, this one is a bit iffy.
There is a Main Skill that increases the Ingredients found while a Pokemon is searching. So, having a Careful Nature for a Pokemon with that ability is very helpful. It's all about getting the right Pokemon with the right Nature.
2 Sassy
Sassy is a Nature that increases Main Skill activation chances while lowering your Pokemon's EXP Gains. Being able to have that Main Skill go off more than normal makes it perfectly fine to reduce any EXP earned. It does depend on the type of Main Skill, though.
You'll want to keep your fingers crossed for the Sassy Nature on a Pokemon with a Main Skill like Metronome, Energizing Cheer S, or Extra Helpful S. Metronome uses a randomly chosen Main Skill, Energizing Cheer S delivers energy to random Pokemon, and Extra Helpful makes a helper Pokemon four times more helpful. Gaining access to those more often is amazing.
1 Gentle
The last Pokemon Sleep Nature that increases your chances of using a Main Skill is Gentle. Energy Recovery is the statistic that sees reduction with this one. If you've got an energy restoring Main Skill, the Gentle Nature is the perfect choice. It will keep your Pokemon active all day long.
In addition to Main Skills, Pokemon have some skills as a specialty. If a Pokemon specializes in Skills, they have a higher chance of using their Main Skill when a part of your team. With the boost of Main Skill chances by the Gentle Nature, that's an even further increase of Main Skill availability to keep your team busy and happy.